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Recently, the Indian Institute of Technology (IIT) Kanpur signed a Memorandum of Understanding (MoU) with Canada based biotechnology company (Conlis Global) for licensing of an innovative and indigenously developed technology that promotes bone healing and regeneration or Bone Grafting.

What are Nano Hydroxyapatite-based Porous Composite Scaffolds?

About:

• The Nano Hydroxyapatite-based Porous Composite Scaffolds are biodegradable and have osteoinductive and osteopromotive properties for bone regeneration.
• It is highly biocompatible ensuring good cell material interaction with osteoblast cells exhibiting a high mechanical strength and
• interaction between the polymer network and the solvent.

Characteristics:

• It has osteoinductive and osteopromotive properties due to which it has bone healing and bone growth characteristics.
• They are highly biocompatible, resulting in good cell material interaction with osteoblast cells exhibiting a high mechanical strength and interaction between the polymer network and the solvent.
• Osteoblast cells are responsible for mineralisation of bone during bone formation and bone remodelling.

Applications:

• It is commonly used in orthopaedic and dental implants, bone graft substitutes, coatings for prosthetic devices, and tissue engineering scaffolds.
• Functionalized scaffolds can be used as fillers in large-size bone defects, without compromising the connectivity and structural defects, oxygen, and blood circulation.
• It enhances tissue formation, mineralization, and rapid defect healing.

What is Bone Grafting?

About:

• Bone grafting involves a surgical technique where transplanted bone is utilised to repair and reconstruct bones affected by disease or injury.
• This procedure is applicable for repairing bones throughout the body.
• Surgeons may harvest bone from various sources such as the hips, legs, or ribs for grafting purposes.

Objective:

• The primary objective of the invention is to overcome the drawbacks of the existing remedies.
• This technology provides the delivery of bone active molecules, antibiotics or any other drug for combating bone
• pathologies, reconstruction of irregular bone defects and for dental applications as well.

Functions:

• The technology facilitates bone regeneration in a biocompatible manner by acting as a carrier for bone- active biomolecules, delivering them directly to the site of an implant.
• The material is a promising approach for reconstructing and repairing bone defects while addressing the drawbacks and complications associated with technologies that are available in the market at present.
• The functionalized scaffolds can be used as fillers in large size bone defects, without compromising the connectivity and structural defects, oxygen and blood circulation thereby enhancing tissue formation, mineralisation, and rapid defect healing.
• It can also be used as a bone substitute, overcoming autograft limitations.

Read also: Stem Cells